Increased dosages of inhaled corticosteroids

Inhaled steroids are ordinarily recommended to cure inviduals that experience early asthma complications.
According to certain recent researches, one may enhance the standard dosage of inhaled corticosteroids by eight times, but benefits will be not enhanced in such situation. Ejaz Yousef, an expert that has been involved in these researches, claims that if a doctor sees that medical position of a patient becomes worse, he/she may indicate using oral steroids instead of increasing the dosage of inhaled steroids. Increasing the measure of inhaled corticosteroids is not without any unwanted response. This factor leads to various side responses. For example, the hypothalamic-pituitary adrenal axis may be suppressed in such case.
Usage of inhaled steroids was considered to be alternative therapy to applying oral medications. It was in 1997. It was recommended to indicate inhaled corticosteroids as alternatives of oral medications that are useful for individuals with asthma complications.
Then, certain researches have displayed that intake of enhanced measures of inhaled steroids systematically doesn’t enhance benefits.
Yousef and his colleagues have conducted a research which involved almost 200 kids of 2-17 years. These kids were cured with inhaled steroids during 3 months. They were chosen randomly for therapies for a period of 12 days. Any kid who suffered from asthma complications was given inhaled corticosteroids. Then the results were evaluated by the scientists.
No any kid that smoked, had symptoms of chronic asthma or lung pathology was implicated in the research.
Patients had to inform about their side reactions via telephone within 72 hours. Thus, it was reported about cough during nighttime, wheeze, shortness of breath and intolerance when it comes to exercises. Every sign was evaluated according to a score which was ranged from 0 to 4. 0 meant no any sigh; 4 meant the highest severity level.
Only 4 kids out of 82 the children that were given increased doses of inhaled corticosteroids had to use systemic corticosteroids. 2 of them were given doubled dosages; others two were applying the dosage that was more increased by 8 times than a normal one.
According to the results of the research, usefulness of the medications, placebo effect, supervision of doctors and treatment of individuals during early stages of asthma exacerbation were responsible for acquiring good results.
This as well as other researches demonstrate that not every story about steroids is related to abuse and administration of them as doping. Steroids are usable for numerous medical purposes.