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среда, 21 декабря 2011 г.

It will be soon possible to bulk up without any side effects

Scientists intend to elaborate alternative preparations to anabolic steroids and other performance-enhancing drugs. They point out that sportspersons may soon have another way to increase muscles. The Salk Institute has claimed that the efforts of the scientists have got success. Recent researches have shown that inactivation of a genome regulator that is known as “NCoR1” causes increase of muscle size, energy and endurance. The leader of the researches conducted in the Salk Institute, Ronald Evans, says that this knowledge may contribute in introduction of some new medications that will benefit not only for athletes and bodybuilders who train but also for persons who are sedentary.
The scientists of the Salk Institute mention about individuals who can’t do physical exercises because they suffer of various health problems, such as diabetes, frailty, immobility and other physical or mental factors that cause sedentarism. The specialists put efforts to develop several specific medications that could benefit for sedentary persons so, as exercises benefit for healthy people. Now they experiment with sedentary mice.
As for anabolic steroids, they can lead to enhancement of muscle size in sedentary people. But people who administrate anabolic steroids must train and modify their diets to reach more essential effects.
If new drugs that block NCoR1 are developed by specialists successfully, they will make significant changes in sedentary people. But could you imagine which benefits will be caused in sportspersons?
But there is also an essential difference between anabolic steroids and NCoR1 suppression. As it is known, anabolic steroids cause side results; some of them can be quite dangerous for health and even for life. Furthermore, anabolic steroids can cause severe unwanted effects especially in women. But as for NCoR1 suppression, specialists assure that preparations which will block this genome regulator will not lead to undesirable symptoms.
There is an article about NCoR1 suppression which has the following title: “NCoR1 Is a Conserved Physiological Modulator of Muscle Mass and Oxidative Function”. It represents results of various experiments that enrolled mice and nematodes. The experiments have displayed that NCoR1 suppression benefits for muscle size significantly. The mice with suppression of this genome regulator had got more induced muscles and ran faster than others.
Unfortunately, the mice with NCoR1 suppression were not compared with the mice that were given anabolic steroids. If these two types of mice were compared, the results of the experiments would be very valuable for further studies and conclusions.
It is possible to notice that elder persons and individuals who have muscle dystrophy will be soon enrolled in studies to find out benefits of new potential preparations.

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